Brainwaves A to Z returns with the “U” episode – all bands or songs starting with “U.”
| Band | Song |
| U2 | Out of Control |
| Ultravox | The Voice |
| The Undertones | Jimmy Jimmy |
| Ugly Kid Joe | Cat’s in the Cradle (cover: Harry Chapin) |
| Undisputed Truth | Smiling Faces Sometimes |
| Usher | Wait for it (soundtrack: Hamilton Mixtape) |
| Utopia | Star Trek theme |
| The Flying Tourbillon Orchestra | Uniform |
| R.E.M. | Underneath the Bunker |
| R.E.M. | Uberlin |
| Talking Heads | Uh-oh, Love Comes to Town |
| Neon Trees | Unavoidable |
| Riff Cohen | Une Femme Assise |
| Death Cab for Cutie | Underneath the Sycamore |
| Matt Pond PA | Used to Be |
| Eels | Ugly Love |
| Brinsley Schwarz | The Ugly Thing |
| Matthew Sweet | The Ugly Truth |
| Charlie Daniels Band | Uneasy Rider |
| Paul & Linda McCartney | Uncle Albert-Admiral Halsey |
| Creedence Clearwater Revival | Up Around the Bend |
| The Guess Who | Undun |
| The Move | Useless Information |
| The War on Drugs | Under the Pressure |
| Thirteen Senses | Under the Sun |
| Lisa Loeb | Underdog |
| Genesis | Undertow |
| Ted Leo & the Pharmacists | Under the Hedge |
| The Witches | Until the Next Pleasure |
| Gin Blossoms | Until I Fall Away |
| The New Pornographers | Unguided |
| The Who | Underture |
